Modifying Effects of Piper longum on Cell Surface Abnormalities in 7, 12-dimethylbenz(A)Anthracene Induced Hamster Buccal Pouch Carcinogenesis
نویسندگان
چکیده
منابع مشابه
Lupeol Protects Abnormalities in Cell Surface Moities during 7, 12-dimethylbenz[a]anthracene Induced Hamster Buccal Pouch Carcinogenesis
Lupeol, a pentacyclic triterpene, possesses diverse pharmacological and biochemical activities including anticancer and antioxidant effects. Abnormalities in the status of glycoconjugates and lipids in the cell results in malignant transformation. The aim of the present study was to investigate the protective effect of lupeol on cell surface glycoconjugates and lipids abnormalities during 7,12-...
متن کاملInduction of Apoptosis by Piper Betel Leaf Extract on 7, 12 Dimethylbenz [a] Anthracene Induced Hamster Buccal Pouch Carcinogenesis
The induction of apoptosis by Piper betel leaf extracts during 7, 12 dimethylbenz [a] anthracene (DMBA) induced hamster buccal pouch (HBP) carcinoma was studied in male Syrian hamsters using DNA fragmentation and the apoptosis-associated proteins, tissue transglutaminase (tTG) and Bcl-2. Hamsters were divided into four groups of six animals each. Animals in group 1 were painted with a 0.5% solu...
متن کاملEnicostemma Littorale Protects Cell Surface Abnormalities during Dmba-induced Hamster Buccal Pouch Carcinogenesis
Glycoconjugates [protein bound hexose, protein bound hexosamine, total sialic acid and fucose] play a pivotal role in neoplastic transformation if they are abnormally expressed. The protective effect of Enicostemma littorale leaves on cell surface abnormalities was analyzed by measuring the status of the above said glycoconjugates during 7,12dimethylbenz(a) anthracene (DMBA) induced hamster buc...
متن کاملTumor Preventive Potential of Cromolyn in 7, 12- Dimethylbenz(a)anthracene Induced Hamster Buccal Pouch Carcinogenesis
Cromolyn explored diverse pharmacological effects including antioxidant, anti-inflammatory and anticancer properties. The cytotoxic or anti-cell proliferative potential of cromolyn has been well documented in various cancer cell lines. To date, there are no studies on the chemopreventive potential of cromolyn against 7,12-dimethylbenz(a)anthracene (DMBA) induced oral carcinogenesis. The chemopr...
متن کاملCortisone and hamster buccal pouch carcinogenesis.
Ninety male Syrian hamsters, 3 months of age, were divided into 6 equal experimental groups of 15 animals. Two groups served as controls for 8and 16-week experimental periods. In the remaining 4 groups, the light buccal pouch was painted 3 times weekly with 9,10-dimethyl-l ,2-benzanthracene (DMBA) and sacrificed at 8 and 16 weeks. One 8-week and one 16-week experimental group were also injected...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Pharmacology
سال: 2007
ISSN: 1811-7775
DOI: 10.3923/ijp.2007.290.294